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INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN
Descriptors Found:
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DeCS
Descriptor
English
:
Interleukin 1 Receptor Antagonist Protein
Descriptor
Spanish
:
Proteína Antagonista del Receptor de Interleucina 1
Descriptor
Portuguese
:
Proteína Antagonista do Receptor de Interleucina 1
Tree Number:
D12.644.276.374.460
D12.776.467.374.460
D23.529.374.460
Definition
English
:
A ligand that binds to but fails to activate the INTERLEUKIN 1 RECEPTOR. It plays an inhibitory
role
in the regulation of
INFLAMMATION
and
FEVER
. Several isoforms of the protein exist due to multiple
ALTERNATIVE SPLICING
of its mRNA.
Pharmacological Action:
Antirheumatic Agents
History Note
English
:
2007
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
52275
Unique Identifier:
D053590
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
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